NCLEX-RN Practice Test 2026 – Complete Exam Prep with Mnemonics

The characteristic identified with melanoma through the ABCDE mnemonic is that of irregular borders. The ABCDE mnemonic is a guideline used to evaluate moles and other skin lesions for signs of melanoma, a serious form of skin cancer.

Each letter stands for a specific feature to assess:

- A for Asymmetry, where one half of the mole does not match the other half.

- B for Border, which indicates that the edges of the mole are irregular, ragged, or blurred.

- C for Color, where the color may not be uniform and can include different shades or hues.

- D for Diameter, noting that melanomas are usually larger than 6mm (about the size of a pencil eraser).

- E for Evolving, meaning the mole changes in size, shape, or color over time.

In this context, the characteristic of "borderline irregular" highlights a critical warning sign in identifying potential melanomas, as smooth and even borders are typically associated with benign moles or lesions. Recognizing irregular borders is essential for early detection and treatment of melanoma.